Responsible lecturer: PD Dr. Vera Hintze
Lecturers: PD Dr. Vera Hintze, Dr. Susanne Bierbaum, Dr. Ute Bergmann, Dr. Poh Soo Lee, Prof. Marie Hubalek Kalbacova
Semester: Winter Semester
Registration for Czech students: via e-mail to matun@ujep.cz
Time and Place, preliminary: Friday, 13:00 – 14:30
Lectures are organized in a hybrid way:
- Online: https://tu-dresden.zoom-x.de/j/62281926074?pwd=cPuM5sAgtxTkeLyRbx3YzmBFGp70xK.1
Meeting-ID: 622 8192 6074
Kenncode: A2=HzD%@ - In presence: 01069 Dresden, Max-Bergmann-Zentrum für Biomaterialien, Schweizer Straße 3, Seminar room
The central topic of the lecture is the processes that take place when biomaterials are contacted by biological systems. Both the causes, the potential biological consequences and in particular the possibilities of influence through surface design on such interfacial processes are dealt with. The relevant foundations of cell communication and cell reaction to biochemical and physical properties are also considered against this background. Various methods of defined design of biomaterial surfaces are explained with particular attention (i) of biological backgrounds, (ii) methods for generating surface states, (iii) the surface properties to be sought and (iv) the cell biological, animal and clinical results. This includes:
- the production of defined morphologies by physical and chemical processes,
- physical/chemical modification of surface properties,
- inorganic coating systems as well as
- the field of BioSurface Engineering, i.e. the biomimetic replica of the native cell environment provided by the extracellular matrix (ECM).
In the latter, the possible uses of various components of the native ECM, (peptides, (structure) proteins, growth factors, glycosaminoglycans, nucleic acids, aptamers) for BioSurface engineering are presented and, depending on substrates and components, the advantages and disadvantages of immobilization strategies are comprehensively presented. This is discussed with examples from the current research of the Chair.
| Date | Content | Lecturers | |
| 18.10.24 | 1 Contents//Interaction processes | Dr. Vera Hintze | |
| 25.10.24 | 2 Physico-chemical modifications | Dr. Vera Hintze | |
| 01.11.24 | 3 Electrochemical methods for surface functionalization I | Dr. Ute Bergmann | |
| 08.11.24 | 4 Morphology | Dr. Vera Hintze | |
| 15.11.24 | 5 Immobilisation strategies | Dr. Vera Hintze | |
| 22.11.24 | 6 Growth factors and cytokines | Dr. Vera Hintze | |
| 29.11.24 | 7 Biofunctionality, cell communication and surfaces | Dr. Susanne Bierbaum | |
| 06.12.24 | 8 BioSurface Engineering – Introduction | Dr. Susanne Bierbaum | |
| 13.12.24 | 9 Nanostructural effects | Prof. Marie Hubalek Kalbacova | |
| 20.12.24 | 10 Extracellular matrix I | Dr. Susanne Bierbaum | |
| 10.01.25 | 11 Extracellular matrix II | Dr. Susanne Bierbaum | |
| 17.01.25 | 12 Electrochemical methods for surface functionalization | Dr. Ute Bergmann | |
| 24.01.25 | 13 Animal models and analytical imaging methods (PSL) | Dr. Poh Soo Lee | |
| 31.01.25 | Seminar | ||
| 07.02.25 | 14 Q & A Exam Preparation |